Male reproductive health as a sentinel for environmental endocrine disruption
نویسندگان
چکیده
منابع مشابه
Male reproductive health as a sentinel for environmental endocrine disruption
Effects of endocrine disruptors on experimental animals and wildlife are well established. Antiandrogens and estrogens cause reproductive disorders, such as cryptorchidism, hypospadias, testicular dysgenesis and subfertility. This raises a natural question whether these disorders in humans are also caused by endocrine disrupters and whether they should alert us of harmful exposures. While we st...
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More than 20 years ago, it was suggested that the normal reproductive development of the male embryo may be aVected by exposure to oestrogens, the focus initially being on the mother’s endogenous oestrogen. In 1993, Sharpe and Skakkebaek proposed the hypothesis that increased oestrogen exposure in early life increases the risk of the two genital malformations hypospadias and cryptorchidism, and...
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The production and widespread use of synthetic chemicals since the 1940s have resulted in ubiquitous contamination of fish, wildlife and human populations. Since the 1960s, observers have documented major damage to wildlife reproduction across the globe, and subsequently, damage to reproductive health in exposed humans as well. The sex ratio in human communities and populations can be readily m...
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Increasing evidence indicates that pollutants may affect the hormone system of humans and wildlife. These endocrine-disrupting chemicals are related to an increased risk of a variety of diseases and disorders, including adverse effects on the reproductive system. By using a sentinel wildlife species, an early warning of adverse health effects due to pollutants in the environment may be provided...
متن کاملEndocrine-disrupting chemicals and male reproductive health.
Endocrine-disrupting chemicals are substances present in the environment that can interfere with normal hormonal balance and thus exert potentially adverse health effects on the human organism. Male reproductive system development and function may be susceptible to the effects of such environmental toxicants. Bisphenol A, phthalates and alkylphenols are important components of multiple products...
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ژورنال
عنوان ژورنال: Acta Veterinaria Scandinavica
سال: 2012
ISSN: 1751-0147
DOI: 10.1186/1751-0147-54-s1-s1